PCSK1N as a Tumor Size Marker and an ER Stress Response Protein in Corticotroph Pituitary Adenomas
PCSK1N is higher in SCA compared with FCA, and associated with corticotroph cell markers and tumor size. PCSK1N is likely to be part of the adaptive response to ER stress, potentially conferring a survival advantage to the corticotroph tumor cell in conjunction with other proteins.
Authors
- Arvind Y. M. Sundaram
- Nicoleta Cristina Olarescu (ORCID: https://orcid.org/0009-0004-9436-539X)
- Kristin Astrid Øystese (ORCID: https://orcid.org/0000-0002-3147-6007)
- Jens Bollerslev (ORCID: https://orcid.org/0000-0002-0654-4610)
- Daniel Dahlberg (ORCID: https://orcid.org/0000-0001-5278-1978)
- Tuula A. Nyman (ORCID: https://orcid.org/0000-0001-8787-5886)
- Jens Petter Berg (ORCID: https://orcid.org/0000-0003-0157-5888)
- Tove Lekva (ORCID: https://orcid.org/0000-0002-7962-4726)
- Kjersti Ringvoll Normann
- Merisa Abusdal (ORCID: https://orcid.org/0009-0001-8460-9117)
Institutions
- Oslo University Hospital (NO)
- OsloMet – Oslo Metropolitan University (NO)
- University of Oslo (NO)
Publication Details
- Journal
- The Journal of Clinical Endocrinology & Metabolism
- Published
- 2024-09-17
- DOI
- https://doi.org/10.1210/clinem/dgae643
- Citations
- 5
- Primary Topic
- Hormonal Regulation and Hypertension
- Type
- article
- Field-Weighted Citation Impact
- 1.79