Healing of a Large Periapical Lesion Using Non-Surgical Root Canal Retreatment: A Case Report

This case report highlights the successful healing of a large periapical lesion through non-surgical root canal retreatment. A 29-year-old male patient presented with a significant radiolucency associated with teeth #21 and #22, initially treated non-surgically. Despite the lesion's size, the treatment, which included thorough canal disinfection and obturation, led to substantial healing. A follow-up cone-beam computed tomography (CBCT) scan after one year confirmed the buccal cortical bone reformation and improvement in the incisive canal area except for the apical region of #21. Subsequently, root canal retreatment was performed for #21. Complete healing was achieved after two years, demonstrating that even extensive periapical lesions can be effectively treated with non-surgical endodontic retreatment, avoiding invasive surgical intervention.