VSV infection and LPS treatment alter serum bile acid profiles, bile acid biosynthesis, and bile acid receptors in mice
This study focuses on the crosstalk between bile acid (BA) metabolism and immune response in VSV infection and LPS treatment models and depicts the effect of infection on circulating BA profiles, the biosynthesis-related enzymes, and their receptors. These findings provide insights into the effect of infection on BA metabolism and signaling, adding a more comprehensive understanding to the relationship between infection, BA metabolism and immune responses.
Authors
- Yangjuan Bai
- Xinhua Dai (ORCID: https://orcid.org/0000-0001-5827-9233)
- Dongmei Zeng (ORCID: https://orcid.org/0000-0002-0007-6203)
- Yunfei An (ORCID: https://orcid.org/0000-0001-9664-1256)
- Chao Wang (ORCID: https://orcid.org/0009-0009-5719-3628)
- Hua Zhang (ORCID: https://orcid.org/0000-0001-6071-0651)
- Yamei Li (ORCID: https://orcid.org/0000-0002-1059-7950)
- Lei Xu (ORCID: https://orcid.org/0000-0001-5518-0510)
- Lin He (ORCID: https://orcid.org/0000-0002-0544-1943)
- Yan Luo (ORCID: https://orcid.org/0000-0003-2985-1768)
Institutions
- Sichuan University (CN)
- West China Hospital of Sichuan University (CN)
- Shanghai Clinical Research Center (CN)
Publication Details
- Journal
- Microbiology Spectrum
- Published
- 2024-09-17
- DOI
- https://doi.org/10.1128/spectrum.00836-24
- Citations
- 1
- Primary Topic
- Drug Transport and Resistance Mechanisms
- Type
- article
- Field-Weighted Citation Impact
- 0.28
Funders
- National Natural Science Foundation of China