Investigation of the toxicity and safety concerns of transgenic maize seeds expressing immunogenic F and HN protein genes against Newcastle disease virus
Overall, no physiological, pathological, or molecular toxicity was observed in the Rats fed with transgenic feed.However, it is important to note that this study focused specifically on the parameters measured and the outcomes observed in Sprague-Dawley rats, and further research and studies are necessary to fully evaluate the safety and potential applications of transgenic edible vaccines in humans or other animals.
Authors
- Aneela Yasmeen (ORCID: https://orcid.org/0000-0002-5478-0263)
- Ibrahim Bala Salisu (ORCID: https://orcid.org/0000-0001-7545-6641)
- Saira Azam (ORCID: https://orcid.org/0000-0002-2064-7093)
- Abdul Qayyum Rao (ORCID: https://orcid.org/0000-0001-9269-3307)
- Sana Shakoor (ORCID: https://orcid.org/0000-0002-4414-5119)
- Muhammad Saad Bhutta (ORCID: https://orcid.org/0000-0002-1721-6807)
- Naila Shahid (ORCID: https://orcid.org/0000-0002-6583-0406)
- Zainab Khursheed
- Sara Ajmal (ORCID: https://orcid.org/0000-0003-4804-5462)
- Ahmad Sheraz
- Ayesha Latif (ORCID: https://orcid.org/0000-0002-7950-4898)
Institutions
- Texas Tech University (US)
- Kinnaird College for Women University (PK)
- University of the Punjab (PK)
- Centre of Excellence in Molecular Biology (PK)
- Government College University, Lahore (PK)
Publication Details
- Journal
- Toxicology Research
- Published
- 2024-09-02
- DOI
- https://doi.org/10.1093/toxres/tfae143
- Citations
- 2
- Primary Topic
- Transgenic Plants and Applications
- Type
- article
- Field-Weighted Citation Impact
- 0.77
Funders
- University of the Punjab