Biophysical modeling of low‐energy ion irradiations with NanOx

We reported in this work an extension of the NanOx biophysical model to consider irradiations with low-energy ions, such as the ones found in TAT and BNCT. The excellent agreement observed at intermediate and high energies between the original hadrontherapy implementation and the present one showed that NanOx offers a consistent, self-integrated framework for describing the biological effects induced by ion irradiations. Future work will focus on the application of the latest version of NanOx to cases closer to the clinical setting.

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Publication Details

Journal
Medical Physics
Published
2024-09-17
DOI
https://doi.org/10.1002/mp.17407
Citations
2
Primary Topic
Radiation Therapy and Dosimetry
Type
article
Field-Weighted Citation Impact
0.84

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article

Biophysical modeling of low‐energy ion irradiations with NanOx

Michaël Beuve, Étienne Testa, Mario Alcocer‐Ávila, R. Delorme et al.
2 citations
Medical Physics
Radiation Therapy and Dosimetry
0.84
article

Biophysical modeling of low‐energy ion irradiations with NanOx

Michaël Beuve, Étienne Testa, Mario Alcocer‐Ávila, R. Delorme, Victor Levrague
article en
2 citations

Abstract

We reported in this work an extension of the NanOx biophysical model to consider irradiations with low-energy ions, such as the ones found in TAT and BNCT. The excellent agreement observed at intermediate and high energies between the original hadrontherapy implementation and the present one showed that NanOx offers a consistent, self-integrated framework for describing the biological effects induced by ion irradiations. Future work will focus on the application of the latest version of NanOx to cases closer to the clinical setting.

Medical PhysicsVol. 51(12)
Université Claude Bernard Lyon 1 (FR), Institut polytechnique de Grenoble (FR), Centre National de la Recherche Scientifique (FR), Institut National de Physique Nucléaire et de Physique des Particules (FR), Laboratoire de Physique Subatomique et de Cosmologie (FR), Université Grenoble Alpes (FR)
Agence Nationale de la Recherche, Institut National de la Santé et de la Recherche Médicale, Université de Lyon, LabEx PRIMES
Affordable and clean energy
Openalex Percentile: Top 24%
Radiation Therapy and Dosimetry
0.84
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Biophysical modeling of low‐energy ion irradiations with NanOx — Michaël Beuve, Étienne Testa, et al. · Medical Physics (2024) | TGRS Research Map | TGRS