Predictive Modeling of Immunogenicity to Botulinum Toxin A Treatments for Glabellar Lines

The study underscores the importance of understanding BoNT-A immunogenicity in clinical practice. By identifying the main predictors of NAb development and differentiating the immunogenic potential of BoNT-A products, the research provides insights for clinicians in optimizing treatment strategies. It highlights the need for careful treatment customization to reduce immunogenic risks, advocating for further research into the mechanisms of BoNT-A immunogenicity.

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Publication Details

Journal
Plastic & Reconstructive Surgery
Published
2024-09-16
DOI
https://doi.org/10.1097/prs.0000000000011748
Citations
7
Primary Topic
Botulinum Toxin and Related Neurological Disorders
Type
article
Field-Weighted Citation Impact
2.58
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article

Predictive Modeling of Immunogenicity to Botulinum Toxin A Treatments for Glabellar Lines

Parinitha Rao, Eqram Rahman, Wolfgang G. Philipp‐Dormston, Jean Carruthers et al.
7 citations
Plastic & Reconstructive Surgery
Botulinum Toxin and Related Neurological Disorders
2.58
article

Predictive Modeling of Immunogenicity to Botulinum Toxin A Treatments for Glabellar Lines

Parinitha Rao, Eqram Rahman, Wolfgang G. Philipp‐Dormston, Jean Carruthers, Richard Webb, Nanze Yu
article en
7 citations

Abstract

The study underscores the importance of understanding BoNT-A immunogenicity in clinical practice. By identifying the main predictors of NAb development and differentiating the immunogenic potential of BoNT-A products, the research provides insights for clinicians in optimizing treatment strategies. It highlights the need for careful treatment customization to reduce immunogenic risks, advocating for further research into the mechanisms of BoNT-A immunogenicity.

Plastic & Reconstructive SurgeryVol. 155(4)
University of British Columbia (CA), Witten/Herdecke University (DE), Chinese Academy of Medical Sciences & Peking Union Medical College (CN), Peking Union Medical College Hospital (CN), UK Research and Innovation (GB), Art Innovation (Netherlands) (NL), Aesthetic Surgery Center (US)
Life in Land
Openalex Percentile: Top 10%
Botulinum Toxin and Related Neurological Disorders
2.58
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