Effect of chronic periodontitis on the endothelial glycocalyx of rat penile corpus cavernosum

Chronic periodontitis can degrade eGlx on the rat penile corpus cavernosum by increasing serum CRP, TNF-α, and IL-6 levels, reducing the p-eNOS/eNOS ratio and the NO concentration in penile cavernous tissue, and resulting in the inhibition of the erectile function. Heparin inhibited eGlx decomposition and improved erectile function in rats with chronic periodontitis.

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Publication Details

Journal
Andrology
Published
2024-09-17
DOI
https://doi.org/10.1111/andr.13765
Citations
3
Primary Topic
Sexual function and dysfunction studies
Type
article
Field-Weighted Citation Impact
1.16
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article

Effect of chronic periodontitis on the endothelial glycocalyx of rat penile corpus cavernosum

Rui Jiang, Yuanhang Xia, Yang Zeng
3 citations
Andrology
Sexual function and dysfunction studies
1.16
article

Effect of chronic periodontitis on the endothelial glycocalyx of rat penile corpus cavernosum

Rui Jiang, Yuanhang Xia, Yang Zeng
article en
3 citations

Abstract

Chronic periodontitis can degrade eGlx on the rat penile corpus cavernosum by increasing serum CRP, TNF-α, and IL-6 levels, reducing the p-eNOS/eNOS ratio and the NO concentration in penile cavernous tissue, and resulting in the inhibition of the erectile function. Heparin inhibited eGlx decomposition and improved erectile function in rats with chronic periodontitis.

AndrologyVol. 13(6)
Southwest Medical University (CN), Affiliated Hospital of Southwest Medical University (CN), Stomatology Hospital (CN)
Good health and well-being
Openalex Percentile: Top 20%
Sexual function and dysfunction studies
1.16
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