Antiviral Effectiveness, Clinical Outcomes, and Artificial Intelligence Imaging Analysis for Hospitalized COVID‐19 Patients Receiving Antivirals
Our study suggests that in real-world studies regarding hospitalized patients with COVID-19 pneumonia, the antiviral effect of nirmatrelvir/ritonavir is significantly superior to azvudine, but the choice of antiviral agents is not necessarily linked to clinical outcomes; the severity of pneumonia at admission is the most important factor to determine prognosis. Additionally, our findings indicate that pulmonary AI imaging analysis can be a powerful tool for predicting patient prognosis and guiding clinical decision-making.
Authors
- Yuan Gao (ORCID: https://orcid.org/0000-0002-0670-9104)
- Hongjun Li
- Zujin Luo (ORCID: https://orcid.org/0000-0002-4417-5422)
- Zhongkai Zhou (ORCID: https://orcid.org/0000-0003-1918-413X)
- Menghua Wu (ORCID: https://orcid.org/0000-0003-0459-3723)
- Liwei Liu (ORCID: https://orcid.org/0000-0002-4133-2816)
- Yunyi Gao (ORCID: https://orcid.org/0000-0002-5041-088X)
- Mengxi Jiang (ORCID: https://orcid.org/0000-0003-4446-984X)
- Zhongjie Hu (ORCID: https://orcid.org/0000-0001-7313-5326)
- Jiaying Zhang (ORCID: https://orcid.org/0009-0000-6855-7823)
- Zhijie Gong (ORCID: https://orcid.org/0009-0004-9767-9423)
- Qiushi Bu
- Yixi Dong
- Lianchun Liang
- Yingmin Ma
- Xinyu Zhang (ORCID: https://orcid.org/0009-0003-2475-4317)
- Wei Wang (ORCID: https://orcid.org/0009-0006-4755-1194)
Institutions
- Qingdao University (CN)
- University of Science and Technology of China (CN)
- Capital Medical University (CN)
- Chinese Academy of Sciences (CN)
- Beijing Chao-Yang Hospital, Capital Medical University (CN)
- Academy of Mathematics and Systems Science (CN)
- Beijing YouAn Hospital (CN)
Publication Details
- Journal
- Influenza and Other Respiratory Viruses
- Published
- 2024-09-01
- DOI
- https://doi.org/10.1111/irv.70006
- Citations
- 1
- Primary Topic
- COVID-19 Clinical Research Studies
- Type
- article
- Field-Weighted Citation Impact
- 0.39