Associations between cuprotosis‐related genes and the spectrum of metabolic dysfunction‐associated fatty liver disease: An exploratory study
GLS may contribute to liver inflammation and fibrosis in MAFLD mainly through cuprotosis and T-cell activation, promoting the progression of MAFLD to HCC. These findings suggest that cuprotosis may play a role in MAFLD progression, potentially providing new insights into MAFLD pathogenesis.
Authors
- Wen‐Yue Liu (ORCID: https://orcid.org/0000-0003-1454-7077)
- Na Tian (ORCID: https://orcid.org/0000-0002-0284-5897)
- Sui‐Dan Chen (ORCID: https://orcid.org/0000-0002-5226-8573)
- Hai‐Yang Yuan
- Meng Zhou (ORCID: https://orcid.org/0000-0001-9987-9024)
- Xin‐Lei Zhang
- Ming‐Hua Zheng (ORCID: https://orcid.org/0000-0003-4984-2631)
- Giovanni Targher (ORCID: https://orcid.org/0000-0002-4325-3900)
- Gang Li (ORCID: https://orcid.org/0009-0002-1976-752X)
- Christopher D. Byrne (ORCID: https://orcid.org/0000-0001-6322-7753)
- Lili Chen (ORCID: https://orcid.org/0009-0009-1960-4158)
- Ke Li (ORCID: https://orcid.org/0000-0002-8790-9561)
- Fudi Wang (ORCID: https://orcid.org/0000-0001-8730-0003)
- Jacob George (ORCID: https://orcid.org/0000-0002-6592-3215)
- Gong Feng (ORCID: https://orcid.org/0000-0001-5394-0029)
- Zi‐Jun Song
- Xin‐Zhe Jin
Institutions
- The University of Sydney (AU)
- Wenzhou Medical University (CN)
- Southampton General Hospital (GB)
- First Affiliated Hospital of Wenzhou Medical University (CN)
- University Hospital Southampton NHS Foundation Trust (GB)
- Westmead Hospital (AU)
- Affiliated Eye Hospital of Wenzhou Medical College (CN)
- Ospedale Sacro Cuore Don Calabria (IT)
- Xi'an Medical University (CN)
- Jining First People's Hospital (CN)
- University of Southampton (GB)
- Zhejiang University (CN)
Publication Details
- Journal
- Diabetes Obesity and Metabolism
- Published
- 2024-09-16
- DOI
- https://doi.org/10.1111/dom.15946
- Citations
- 2
- Primary Topic
- Liver Disease Diagnosis and Treatment
- Type
- article
- Field-Weighted Citation Impact
- 0.77
Funders
- National Health and Medical Research Council