Unveiling the disease progression in developmental and epileptic encephalopathies: Insights from <scp>EEG</scp> and neuropsychology
Our study provides evidence that a clinical progression may appear in genetic DEEs, manifesting as development or worsening of cognitive impairment and disruption of EEG background activity. These results highlight the challenging clinical course and the importance of early intervention and personalized care in the management of patients with DEEs.
Authors
- Costanza Calabrese (ORCID: https://orcid.org/0000-0002-8430-4508)
- Federico Vigevano (ORCID: https://orcid.org/0000-0001-7513-0051)
- Mattia Mercier (ORCID: https://orcid.org/0000-0003-4239-8267)
- Marina Trivisano (ORCID: https://orcid.org/0000-0002-9841-8581)
- Angela De Dominicis (ORCID: https://orcid.org/0000-0002-8526-1511)
- Cinzia Correale (ORCID: https://orcid.org/0000-0002-9302-5412)
- Nicola Specchio (ORCID: https://orcid.org/0000-0002-8120-0287)
- Luigi Mazzone (ORCID: https://orcid.org/0000-0002-5287-3386)
- Giusy Carfì Pavia (ORCID: https://orcid.org/0000-0001-5383-113X)
- Simona Cappelletti (ORCID: https://orcid.org/0000-0003-0738-1240)
- Ludovica Maria Piscitello (ORCID: https://orcid.org/0000-0002-9179-770X)
- Paolo Surdi
Institutions
- University of Rome Tor Vergata (IT)
- Bambino Gesù Children's Hospital (IT)
- IRCCS Ospedale San Raffaele (IT)
- Istituto di Ricovero e Cura a Carattere Scientifico San Raffaele (IT)
Publication Details
- Journal
- Epilepsia
- Published
- 2024-09-17
- DOI
- https://doi.org/10.1111/epi.18127
- Citations
- 8
- Primary Topic
- Epilepsy research and treatment
- Type
- article
- Field-Weighted Citation Impact
- 3.08
Funders
- Ministero della Salute