Quantitative cervicovaginal fluid fetal fibronectin: A liquid biopsy for intra‐amniotic inflammation
Quantitative cervicovaginal fluid fFN with a cut-off of 125 ng/mL had a high sensitivity and a negative predictive value as well as a positive likelihood ratio for the identification of intra-amniotic inflammation. Its high sensitivity and negative predictive value can be used to decrease an index of suspicion of intra-amniotic inflammation. This test may be useful as an initial assessment test to select appropriate patients for amniocentesis to determine intra-amniotic inflammation.
Authors
- Paninee Mongkolsuk
- Rapeewan Settacomkul
- Pornpun Vivithanaporn (ORCID: https://orcid.org/0000-0002-2639-9545)
- Roberto J. Romero (ORCID: https://orcid.org/0000-0002-4448-5121)
- Pisut Pongchaikul (ORCID: https://orcid.org/0000-0001-8757-3554)
- Piya Chaemsaithong (ORCID: https://orcid.org/0000-0003-1750-9834)
- Waranyu Lertrat (ORCID: https://orcid.org/0000-0002-4079-8606)
- Puntabut Warintaksa (ORCID: https://orcid.org/0000-0002-7946-3774)
- Nutnaree Yuenyongdechawat
- Supakorn Chaiyakarn
Institutions
- National Institutes of Health (US)
- University of Liverpool (GB)
- Mahidol University (TH)
- University of Michigan (US)
- Ramathibodi Hospital (TH)
- Eunice Kennedy Shriver National Institute of Child Health and Human Development (US)
- Michigan State University (US)
Publication Details
- Journal
- Acta Obstetricia Et Gynecologica Scandinavica
- Published
- 2024-09-17
- DOI
- https://doi.org/10.1111/aogs.14899
- Citations
- 1
- Primary Topic
- Preterm Birth and Chorioamnionitis
- Type
- article
- Field-Weighted Citation Impact
- 0.39