Urinary extracellular vesicles as a monitoring tool for renal damage in patients not meeting criteria for chronic kidney disease
Alterations in the EV-mediated molecular profile are evident before pathological ACR levels are reached. Direct quantitation of SLC27A2 and AMN in uEVs helps identifying normoalbuminuric subjects with higher cardiorenal risk in early monitoring of CKD.
Authors
- Gema Ruiz‐Hurtado (ORCID: https://orcid.org/0000-0003-3482-0915)
- Juan Antonio López (ORCID: https://orcid.org/0000-0002-9097-6060)
- Aranzazu Santiago‐Hernandez
- J. Segura (ORCID: https://orcid.org/0000-0003-4677-9526)
- Ariadna Martín-Blázquez (ORCID: https://orcid.org/0000-0002-4205-3499)
- Luís M. Ruilope (ORCID: https://orcid.org/0000-0001-6278-7951)
- Nerea Lago‐Baameiro (ORCID: https://orcid.org/0000-0003-1257-4856)
- Marta Martin‐Lorenzo (ORCID: https://orcid.org/0000-0002-0950-3558)
- María Pardo (ORCID: https://orcid.org/0000-0002-9967-1650)
- María G. Barderas (ORCID: https://orcid.org/0000-0003-4290-4721)
- Gloria Álvarez‐Llamas (ORCID: https://orcid.org/0000-0002-3313-721X)
- Miriam Anfaiha‐Sanchez (ORCID: https://orcid.org/0009-0007-2984-6121)
- Jesús Vázquez (ORCID: https://orcid.org/0000-0003-1461-5092)
Institutions
- Universidad Complutense de Madrid (ES)
- Spanish National Centre for Cardiovascular Research (ES)
- Centro de Investigación en Red en Enfermedades Cardiovasculares (ES)
- Complejo Hospitalario Universitario de Santiago (ES)
- Hospital Universitario 12 De Octubre (ES)
- Hospital Universitario Fundación Jiménez Díaz (ES)
- Hospital Nacional de Parapléjicos (ES)
- Universidad Autónoma de Madrid (ES)
- Universidad Europea de Madrid (ES)
Publication Details
- Journal
- Journal of Extracellular Biology
- Published
- 2024-09-01
- DOI
- https://doi.org/10.1002/jex2.170
- Citations
- 3
- Primary Topic
- Extracellular vesicles in disease
- Type
- article
- Field-Weighted Citation Impact
- 0.70
Funders
- Fundación Mutua Madrileña
- “la Caixa” Foundation
- Comunidad de Madrid
- Ministerio de Ciencia, Innovación y Universidades
- Fundación Conchita Rábago
- Instituto de Salud Carlos III
- European Regional Development Fund