A pilot study: Examining cytoskeleton gene expression profiles in Pakistani children with autism spectrum disorder
Here we report the role of cytoskeleton linked genes (PFN and ERM) in co-relation to ASD. Furthermore, variable yet significant quantitative expression of these genes successfully predicted drug-gene interactions as shown with the help of connectivity maps that can be used to support the clinical use of these drugs to treat individuals with ASD in future studies.
Authors
- Ahmed M. Mehdi (ORCID: https://orcid.org/0000-0002-9300-2341)
- Deeba Noreen Baig (ORCID: https://orcid.org/0000-0001-8362-2857)
- Syed Aoun Ali (ORCID: https://orcid.org/0000-0002-4970-694X)
- Sana Malik (ORCID: https://orcid.org/0000-0003-1373-9747)
- Shahid Bashir (ORCID: https://orcid.org/0000-0001-6286-6895)
- Amir Raza
Institutions
- Translational Research Institute (AU)
- The University of Queensland (AU)
- The University of Western Australia (AU)
- Forman Christian College (PK)
- King Fahad Specialist Hospital (SA)
- University of Management and Technology (PK)
Publication Details
- Journal
- International Journal of Developmental Neuroscience
- Published
- 2024-09-17
- DOI
- https://doi.org/10.1002/jdn.10372
- Primary Topic
- Autism Spectrum Disorder Research
- Type
- article
- Field-Weighted Citation Impact
- 0.00