Utility of interleukin‐6 to identify serious bacterial infections in febrile infants aged ≤60 days

Interleukin-6 showed high sensitivity and NPV, which might assist in identifying SBIs early in febrile infants. However, IL-6 was not shown to be superior to CRP and further studies are needed to investigate whether IL-6 should be incorporated in clinical management.

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Publication Details

Journal
Acta Paediatrica
Published
2024-09-17
DOI
https://doi.org/10.1111/apa.17422
Primary Topic
Neonatal and Maternal Infections
Type
article
Field-Weighted Citation Impact
0.00
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article

Utility of interleukin‐6 to identify serious bacterial infections in febrile infants aged ≤60 days

Kristina Elfving, Ioannis Orfanos, Emilie Thorén Krusell
Acta Paediatrica
Neonatal and Maternal Infections
article

Utility of interleukin‐6 to identify serious bacterial infections in febrile infants aged ≤60 days

Kristina Elfving, Ioannis Orfanos, Emilie Thorén Krusell
article en

Abstract

Interleukin-6 showed high sensitivity and NPV, which might assist in identifying SBIs early in febrile infants. However, IL-6 was not shown to be superior to CRP and further studies are needed to investigate whether IL-6 should be incorporated in clinical management.

Acta PaediatricaVol. 114(1)
Lund University (SE), Sahlgrenska University Hospital (SE), Skåne University Hospital (SE), University of Gothenburg (SE)
Good health and well-being
Openalex Percentile: Top 77%
Neonatal and Maternal Infections
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