An MRI-based radiomics nomogram to predict progression-free survival in patients with endometrial cancer
<b>Aim:</b> This study aimed to explore the importance of an MRI-based radiomics nomogram in predicting the progression-free survival (PFS) of endometrial cancer.<b>Methods:</b> Based on clinicopathological and radiomic characteristics, we established three models (clinical, radiomics and combined model) and developed a nomogram for the combined model. The Kaplan-Meier method was utilized to evaluate the association between nomogram-based risk scores and PFS.<b>Results:</b> The nomogram had a strong predictive ability in calculating PFS with areas under the curve (ROC) of 0.905 and 0.901 at 1 and 3 years, respectively. The high-risk groups identified by the nomogram-based scores had shorter PFS compared with the low-risk groups.<b>Conclusion:</b> The radiomics nomogram has the potential to serve as a noninvasive imaging biomarker for predicting individual PFS of endometrial cancer.
Authors
- Caihong Liang (ORCID: https://orcid.org/0000-0002-8882-1967)
- Yujiao Zhao (ORCID: https://orcid.org/0000-0002-5873-3659)
- Xiaodong Ji (ORCID: https://orcid.org/0000-0001-5941-5989)
- L Huang
- Jinxia Zhu
- Wen Shen (ORCID: https://orcid.org/0000-0002-8466-2989)
- Xiangfeng Xu (ORCID: https://orcid.org/0000-0002-4597-9481)
- Zhiyi Song
- Ling Liu
Institutions
- Tianjin University of Traditional Chinese Medicine (CN)
- Nankai University (CN)
- Tianjin First Center Hospital (CN)
- Wuqing District People's Hospital (CN)
- Health First (US)
- Tianjin Central Hospital of Gynecology Obstetrics (CN)
- Siemens Healthcare (United States) (US)
- Campbell Collaboration (NO)
- Indiana University School of Medicine
- Siemens (China) (CN)
- Tianjin Medical University (CN)
Publication Details
- Journal
- Future Oncology
- Published
- 2024-09-17
- DOI
- https://doi.org/10.1080/14796694.2024.2398984
- Primary Topic
- Radiomics and Machine Learning in Medical Imaging
- Type
- article
- Field-Weighted Citation Impact
- 0.00
Funders
- National Natural Science Foundation of China
- Natural Science Foundation of Tianjin City