Therapeutic efficiency of Tamoxifen/Orlistat nanocrystals against solid ehrlich carcinoma via targeting TXNIP/HIF1-α/MMP-9/P27 and BAX/Bcl2/P53 signaling pathways
The developed Tamoxifen/Orlistat nanocrystals combination could be considered a promising approach to augment antitumor effects.
Authors
- Hebatallah M. Saad (ORCID: https://orcid.org/0000-0001-9555-7300)
- Maysa M. F. El‐Nagar (ORCID: https://orcid.org/0000-0001-5807-1117)
- Badriyah Shadid Alotaibi (ORCID: https://orcid.org/0000-0002-4066-5694)
- Ghaleb A. Oriquat (ORCID: https://orcid.org/0000-0003-4443-628X)
- Hanaa A. Ibrahim (ORCID: https://orcid.org/0000-0002-9278-314X)
- Thanaa A. El‐Masry
- Enas I. El Zahaby
Institutions
- Al-Ahliyya Amman University (JO)
- Princess Nourah bint Abdulrahman University (SA)
- Tanta University (EG)
- Egypt Nanotechnology Center (EG)
- Delta University for Science and Technology (EG)
Publication Details
- Journal
- Biomedicine & Pharmacotherapy
- Published
- 2024-09-17
- DOI
- https://doi.org/10.1016/j.biopha.2024.117429
- Citations
- 20
- Primary Topic
- Cancer, Lipids, and Metabolism
- Type
- article
- Field-Weighted Citation Impact
- 5.70