Chemogenetic Activation of RFRP Neurons Reduces LH Pulse Frequency in Female but not Male Mice

These data show for the first time that activation of neurons that have expressed <i>Rfrp</i>, or of a subset of adult RFRP neurons, can independently suppress LH pulsatility in female, but not male mice.

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Publication Details

Journal
Journal of the Endocrine Society
Published
2024-09-17
DOI
https://doi.org/10.1210/jendso/bvae159
Primary Topic
Hypothalamic control of reproductive hormones
Type
article
Field-Weighted Citation Impact
0.00

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article

Chemogenetic Activation of RFRP Neurons Reduces LH Pulse Frequency in Female but not Male Mice

Karl J. Iremonger, Caroline Decourt, Greg M. Anderson, India L Sawyer et al.
Journal of the Endocrine Society
Hypothalamic control of reproductive hormones
article

Chemogenetic Activation of RFRP Neurons Reduces LH Pulse Frequency in Female but not Male Mice

Karl J. Iremonger, Caroline Decourt, Greg M. Anderson, India L Sawyer, Asha Mamgain, Maggie C. Evans
article en

Abstract

These data show for the first time that activation of neurons that have expressed <i>Rfrp</i>, or of a subset of adult RFRP neurons, can independently suppress LH pulsatility in female, but not male mice.

Journal of the Endocrine SocietyVol. 8(11)
University of Otago (NZ)
Royal Society Te Apārangi, Marsden Fund
Good health and well-being
Openalex Percentile: Top 77%
Hypothalamic control of reproductive hormones
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