<scp>DORA</scp>: 48‐week weight and metabolic changes in Black women with <scp>HIV</scp>, in a phase IIIb switch study from dolutegravir‐ or efavirenz‐ to doravirine‐based first‐line antiretroviral therapy

Our findings suggest that a switch to doravirine from efavirenz or dolutegravir is safe and effective in Black women, with significant improvement in lipid profiles, but does not arrest progressive weight gain.

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Publication Details

Journal
HIV Medicine
Published
2024-09-17
DOI
https://doi.org/10.1111/hiv.13711
Citations
4
Primary Topic
HIV-related health complications and treatments
Type
article
Field-Weighted Citation Impact
2.76

Funders

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article

DORA: 48‐week weight and metabolic changes in Black women with HIV, in a phase IIIb switch study from dolutegravir‐ or efavirenz‐ to doravirine‐based first‐line antiretroviral therapy

Michelle Moorhouse, Joana Woods, Simiso Mandisa Sokhela, François Venter et al.
4 citations
HIV Medicine
HIV-related health complications and treatments
2.76
article

DORA: 48‐week weight and metabolic changes in Black women with HIV, in a phase IIIb switch study from dolutegravir‐ or efavirenz‐ to doravirine‐based first‐line antiretroviral therapy

Michelle Moorhouse, Joana Woods, Simiso Mandisa Sokhela, François Venter, Karlien Möller, Bronwyn Bosch, Andrew Hill, Godspower Akpomiemie, Esther Bhaskar, Nomathemba Chandiwana, Chelsea Kruger, Ncomeka Manentsa, Philadelphia Macholo, Noxolo Tom
article en
4 citations

Abstract

Our findings suggest that a switch to doravirine from efavirenz or dolutegravir is safe and effective in Black women, with significant improvement in lipid profiles, but does not arrest progressive weight gain.

HIV MedicineVol. 26(1)
University of Liverpool (GB), University of the Witwatersrand (ZA), University of Pretoria (ZA)
United States Agency for International Development, Bill and Melinda Gates Foundation, Gilead Sciences, Children's Investment Fund Foundation, ViiV Healthcare, MSD K.K., Medical Research Council
Good health and well-being
Openalex Percentile: Top 10%
HIV-related health complications and treatments
2.76
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