Cardiac angiosarcoma with lung metastasis presented with multiple halo signs: One case report and literature review

Cardiac angiosarcoma is a rare aggressive malignancy with rapid progress and poor prognosis. Here we report 1 patient with cardiac angiosarcoma with lung metastasis, which presented as multiple halo signs and ground glass opacities. The patient underwent computed tomography (CT) guided lung biopsy and postoperative tissue histology confirmed the diagnosis of angiosarcoma. Transthoracic echocardiography (TTE) and cardiac Magnetic Resonance Imaging (MRI) identified the main tumor in the right atrium. Positron emission tomography/computed tomography (PET/CT) excluded intraabdominal lesions. The patient was given chemotherapy with nab-paclitaxel, cardiac radiation therapy and remained follow-up. Considering the rapid disease progression and poor prognosis, the present case report is intended to provide diagnostic insight into cardiac angiosarcoma with lung metastasis, especially with lung CT scans of multiple halo signs and ground glass opacities.