Fatal Mucormycosis in a Diabetic Patient: A Case Report and Review of Diagnostic Challenges

Mucormycosis (zygomycosis) is a severe and often fatal mycotic infection affecting primarily immunocompromised individuals. A 61-year-old female with type 2 diabetes mellitus and end-stage renal disease developed septic shock in association with mucormycosis. Despite antifungal treatment with liposomal amphotericin B, the patient's condition rapidly deteriorated, leading to death within 48 hours. This case underscores the aggressive nature of mucormycosis, highlighting the necessity for early diagnosis using advanced diagnostic tools and prompt treatment to improve patient outcomes.

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Journal
Cureus
Published
2024-09-16
DOI
https://doi.org/10.7759/cureus.69546
Primary Topic
Antifungal resistance and susceptibility
Type
article
Field-Weighted Citation Impact
0.00
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article

Fatal Mucormycosis in a Diabetic Patient: A Case Report and Review of Diagnostic Challenges

Allison Cruse, John D. Overton, Caitlin Noble, Sumit Sontakke et al.
Cureus
Antifungal resistance and susceptibility
article

Fatal Mucormycosis in a Diabetic Patient: A Case Report and Review of Diagnostic Challenges

Allison Cruse, John D. Overton, Caitlin Noble, Sumit Sontakke, Robert A. Burrow, Poonam Sharma, W. Berlin, Robert T Brodell, Ariel Velasquez
article en

Abstract

Mucormycosis (zygomycosis) is a severe and often fatal mycotic infection affecting primarily immunocompromised individuals. A 61-year-old female with type 2 diabetes mellitus and end-stage renal disease developed septic shock in association with mucormycosis. Despite antifungal treatment with liposomal amphotericin B, the patient's condition rapidly deteriorated, leading to death within 48 hours. This case underscores the aggressive nature of mucormycosis, highlighting the necessity for early diagnosis using advanced diagnostic tools and prompt treatment to improve patient outcomes.

CureusVol. 16(9)
Jackson Memorial Hospital (US), University of Mississippi Medical Center (US), Ross University School of Medicine (BB)
Good health and well-being
Openalex Percentile: Top 81%
Antifungal resistance and susceptibility
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Fatal Mucormycosis in a Diabetic Patient: A Case Report and Review of Diagnostic Challenges — Allison Cruse, John D. Overton, et al. · Cureus (2024) | TGRS Research Map | TGRS