Evaluation of Antioxidant and Anti-hyperlipidemic Effect of Tridax Procumbens L. Flower Extract by in Vitro Method

This study assessed the in vitro antioxidant and anti-hyperlipidemic properties of Tridax procumbens Linn methanolic and hydro alcoholic flower extract. The amount of antioxidant activity was measured using techniques including DPPH (2, 2-diphenyl-2-picryl hydroxyl) and nitric oxide. We analyzed the percentage of different free radicals that were scavenged using ascorbic acid, a common antioxidant. Using the TBARS assay and lipid peroxidation measurements, the extracts anti-hyperlipidemic potential was also assessed. Furthermore, the phytochemical analysis of the floral extracts that were methanolic and hydroalcoholic revealed the presence of flavonoids, phenols, saponins, terpenoids, triterpenes, alkaloids, glycosides, and tannins in substantial amounts. Significant antioxidant activity was found (P<0.001) for DPPH scavenging at various flower extract doses. The methanolic extract's IC50 value and % inhibition were higher than hydro-alcoholic extracts.

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Publication Details

Journal
International Journal For Multidisciplinary Research
Published
2024-09-14
DOI
https://doi.org/10.36948/ijfmr.2024.v06i05.27316
Primary Topic
Pharmacology and Nanomedicine Research
Type
article
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article

Evaluation of Antioxidant and Anti-hyperlipidemic Effect of Tridax Procumbens L. Flower Extract by in Vitro Method

P - Pradeepa, N L Gowrishankar -, Sony Priya P D -, K P - Chandana et al.
International Journal For Multidisciplinary Research
Pharmacology and Nanomedicine Research
article

Evaluation of Antioxidant and Anti-hyperlipidemic Effect of Tridax Procumbens L. Flower Extract by in Vitro Method

P - Pradeepa, N L Gowrishankar -, Sony Priya P D -, K P - Chandana, Rafna Femi -, Swathi Sivan -, M R - Sreelakshmi
article en

Abstract

This study assessed the in vitro antioxidant and anti-hyperlipidemic properties of Tridax procumbens Linn methanolic and hydro alcoholic flower extract. The amount of antioxidant activity was measured using techniques including DPPH (2, 2-diphenyl-2-picryl hydroxyl) and nitric oxide. We analyzed the percentage of different free radicals that were scavenged using ascorbic acid, a common antioxidant. Using the TBARS assay and lipid peroxidation measurements, the extracts anti-hyperlipidemic potential was also assessed. Furthermore, the phytochemical analysis of the floral extracts that were methanolic and hydroalcoholic revealed the presence of flavonoids, phenols, saponins, terpenoids, triterpenes, alkaloids, glycosides, and tannins in substantial amounts. Significant antioxidant activity was found (P<0.001) for DPPH scavenging at various flower extract doses. The methanolic extract's IC50 value and % inhibition were higher than hydro-alcoholic extracts.

International Journal For Multidisciplinary ResearchVol. 6(5)
Openalex Percentile: Top 96%
Pharmacology and Nanomedicine Research
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