<scp>Placental growth factor</scp> alleviates hyperglycemia‐induced trophoblast pyroptosis by regulating mitophagy
PLGF inhibited hyperglycemia, while PLGF reversed hyperglycemic injury by promoting mitophagy via the BNIP3/PINK1/Parkin pathway. Altogether, these results suggest that PLGF may protect against trophoblast dysfunction in diabetes.
Authors
- Zitong Cao
- Peng Wu (ORCID: https://orcid.org/0000-0002-7440-074X)
- Jun Meng (ORCID: https://orcid.org/0000-0002-7633-3624)
- Zuo Wang
- Lu He (ORCID: https://orcid.org/0000-0002-7367-2452)
- Jun Tao
- Yuzhu Rao (ORCID: https://orcid.org/0009-0006-4923-247X)
- Shiming Tan
- Jinli Zhao
- Jingjing Wang (ORCID: https://orcid.org/0000-0002-8760-8822)
Institutions
- First Affiliated Hospital of University of South China (CN)
- Hengyang Academy of Agricultural Sciences (CN)
- University of South China (CN)
Publication Details
- Journal
- Journal of obstetrics and gynaecology research
- Published
- 2024-09-17
- DOI
- https://doi.org/10.1111/jog.16050
- Citations
- 6
- Primary Topic
- Pregnancy and preeclampsia studies
- Type
- article
- Field-Weighted Citation Impact
- 3.50
Funders
- Natural Science Foundation of Hunan Province