A Rare Cause of a Growing Solitary Pulmonary Nodule

Solitary pulmonary nodules are common on chest imaging, from lung cancer screening computed tomography scans to incidental findings on examinations performed for other reasons. Here, a 76-year-old man presented to the emergency department with fevers and cough, and computed tomography scan of the chest revealed a left upper-lobe consolidation and a 15-mm right lower-lobe nodule. The consolidation resolved with antibiotics; however, the nodule slowly grew over 2 years. Subsequent biopsy findings revealed neoplastic-appearing lymphoid cells with immunohistochemistry stains consistent with primary pulmonary mucosa-associated lymphoid tissue lymphoma. Given the slow growth of this neoplasm, the patient was managed with active surveillance.