Prevalent Metformin Use in Adults With Diabetes and the Incidence of Long COVID: An EHR-Based Cohort Study From the RECOVER Program
Prevalent metformin use is associated with a slightly lower incidence of death or PASC after SARS-CoV-2 infection. PASC incidence by computable phenotype is higher than by EHR code, especially in PCORnet. These data are consistent with other observational analyses showing prevalent metformin is associated with favorable outcomes after SARS-CoV-2 infection in adults with T2DM.
Authors
- Grace A. McComsey (ORCID: https://orcid.org/0000-0003-2690-8888)
- Mark G. Weiner (ORCID: https://orcid.org/0000-0001-5586-9940)
- Carolyn T. Bramante (ORCID: https://orcid.org/0000-0001-5858-2080)
- Talia D. Wiggen (ORCID: https://orcid.org/0000-0002-5234-3238)
- John B. Buse (ORCID: https://orcid.org/0000-0002-9723-3876)
- Sajjad Abedian (ORCID: https://orcid.org/0000-0002-0411-5185)
- Colby Lewis (ORCID: https://orcid.org/0000-0001-5765-0352)
- Til Stürmer (ORCID: https://orcid.org/0000-0002-9204-7177)
- Rainu Kaushal (ORCID: https://orcid.org/0000-0002-4694-2517)
- Steve Johnson (ORCID: https://orcid.org/0000-0002-2983-6384)
- Clifford J. Rosen (ORCID: https://orcid.org/0000-0003-3436-8199)
- Jonathan Arnold
- Praveen C. Mudumbi (ORCID: https://orcid.org/0000-0003-3792-1789)
- Jared D. Huling (ORCID: https://orcid.org/0000-0003-0670-4845)
- Rachel Wong (ORCID: https://orcid.org/0000-0003-3108-7324)
- Shari B. Brosnahan (ORCID: https://orcid.org/0000-0002-2092-3633)
- Shawn N. Murphy
- Kristine M. Erlandson
Institutions
- University of North Carolina at Chapel Hill (US)
- University of Minnesota (US)
- University of Pittsburgh (US)
- Cornell University (US)
- MaineHealth (US)
- Weill Cornell Medicine (US)
- Mass General Brigham (US)
- University of Colorado Anschutz Medical Campus (US)
- New York University (US)
- Case Western Reserve University (US)
- Stony Brook University (US)
Publication Details
- Journal
- Diabetes Care
- Published
- 2024-09-17
- DOI
- https://doi.org/10.2337/dca24-0032
- Citations
- 10
- Primary Topic
- COVID-19 Clinical Research Studies
- Type
- article
- Field-Weighted Citation Impact
- 3.89
Funders
- National Institute on Aging
- National Heart, Lung, and Blood Institute
- National Institute of Diabetes and Digestive and Kidney Diseases
- National Center for Advancing Translational Sciences