Altered Cell Clusters and Upregulated Aqp1 in Connexin 50 Knockout Lens Epithelium
Lens epithelial cells exhibit an intrinsic heterogeneity of different cell clusters in regulating lens homeostasis and lens growth. Upregulated Aqp1 in Cx50KO lens epithelial cells suggests that both connexin 50 and AQP1 likely play important roles in regulating water homeostasis in lens epithelial cells.
Authors
- Xiaohua Gong (ORCID: https://orcid.org/0000-0003-2074-1802)
- William Lin
- Guangdu Jack Shang
- Haiwei Zhang
- Chun‐hong Xia
- Xinfang Xing
- Rachel W. Li (ORCID: https://orcid.org/0000-0002-8112-4237)
Institutions
- University of California, Berkeley (US)
Publication Details
- Journal
- Investigative Ophthalmology & Visual Science
- Published
- 2024-09-17
- DOI
- https://doi.org/10.1167/iovs.65.11.27
- Citations
- 3
- Primary Topic
- Connexins and lens biology
- Type
- article
- Field-Weighted Citation Impact
- 0.70