The 1400 metabolite‐mediated relationship between 91 inflammatory cytokines and migraine: An exploratory two‐step Mendelian randomization study
Our research findings provide evidence for both a causal connection between inflammatory cytokines and migraines, as well as a metabolite-mediated pathway. These biomarkers facilitate the detection, diagnosis and treatment of migraines while offering fresh perspectives on their underlying mechanisms.
Authors
- Hongxiu Lu
- Yue Shen (ORCID: https://orcid.org/0000-0002-3276-7295)
- Dongbin Zhang (ORCID: https://orcid.org/0000-0002-7179-101X)
- Xutong Lv
- Huiqi Sun
Institutions
- Shandong University of Traditional Chinese Medicine (CN)
- Affiliated Hospital of Shandong University of Traditional Chinese Medicine (CN)
Publication Details
- Journal
- European Journal of Clinical Investigation
- Published
- 2024-09-15
- DOI
- https://doi.org/10.1111/eci.14316
- Citations
- 2
- Primary Topic
- Migraine and Headache Studies
- Type
- article
- Field-Weighted Citation Impact
- 0.77
Funders
- National Natural Science Foundation of China
- Natural Science Foundation of Shandong Province