Longitudinal analysis of peripheral immune cells in patients with multiple sclerosis treated with anti‐CD20 therapy
The findings of this study elucidate phenotypic clusters of NK and CD8<sup>+</sup> T cells, which have previously been underexplored in the context of anti-CD20 therapy. Phenotypic modifications towards a more regulatory and controlled phenotype suggest that these subpopulations may play a critical and previously unrecognized role in mediating the therapeutic efficacy of anti-CD20 treatments.
Authors
- Maria L. Elkjaer (ORCID: https://orcid.org/0000-0002-8596-142X)
- Lasse Frank Voss (ORCID: https://orcid.org/0000-0003-0904-6753)
- Zsolt Illés (ORCID: https://orcid.org/0000-0001-9655-0450)
- Jesper Bonnet Moeller (ORCID: https://orcid.org/0000-0001-8786-8037)
- Mie Waede (ORCID: https://orcid.org/0000-0002-7458-9597)
- Christina Kingo
Institutions
- Universität Hamburg (DE)
- University of Southern Denmark (DK)
- Odense University Hospital (DK)
- Technical University of Denmark (DK)
Publication Details
- Journal
- Annals of Clinical and Translational Neurology
- Published
- 2024-09-15
- DOI
- https://doi.org/10.1002/acn3.52182
- Citations
- 4
- Primary Topic
- Multiple Sclerosis Research Studies
- Type
- article
- Field-Weighted Citation Impact
- 1.70
Funders
- Scleroseforeningen
- Jascha Fonden
- Lundbeckfonden
- Novo Nordisk