Diagnostic potential of <i>SDHB</i> mRNA contained in serum extracellular vesicles among patients with prostate cancer
The levels of OXPHOS-related mRNAs in EVs correlated with those in PC tissue, among which SDHB mRNA was found to be a novel biomarker to diagnose ARSI-resistance. EV-SDHB may be useful for early diagnosis of ARSI-resistance.
Authors
- Hiroyasu Ito (ORCID: https://orcid.org/0000-0002-4836-4001)
- Yasuhiro Sakai (ORCID: https://orcid.org/0000-0001-7210-9249)
- Kosuke Mizutani (ORCID: https://orcid.org/0000-0001-5767-5314)
- Kyojiro Kawakami (ORCID: https://orcid.org/0000-0002-2822-3252)
- Yasunori Fujita (ORCID: https://orcid.org/0009-0006-0334-7212)
- Eiji Sugihara (ORCID: https://orcid.org/0000-0002-3233-1045)
- Hidetoshi Ehara
- Tatsuya Ando (ORCID: https://orcid.org/0000-0002-2469-7266)
- Shohei Toyota
- Taku Kato (ORCID: https://orcid.org/0000-0002-3261-1434)
- Kouhei Sakurai (ORCID: https://orcid.org/0000-0003-2428-0310)
- Masafumi Ito (ORCID: https://orcid.org/0000-0002-3553-4104)
- Yuko Hata
Institutions
- Asahi University (JP)
- Fujita Health University (JP)
- Hamamatsu University School of Medicine (JP)
- Saitama International Medical Center (JP)
- Tokyo Metropolitan Institute of Gerontology (JP)
Publication Details
- Journal
- The Prostate
- Published
- 2024-09-15
- DOI
- https://doi.org/10.1002/pros.24792
- Citations
- 2
- Primary Topic
- Prostate Cancer Treatment and Research
- Type
- article
- Field-Weighted Citation Impact
- 0.84
Funders
- Japan Society for the Promotion of Science