Detection Of CCR5 Delta-32 Mutation Using High-Resolution Melting Curve Analysis: Challenges and Facts
The HRM test identified four samples with heterozygote mutations in each HIV-infected (8.89%) and control (5.72%) groups. More importantly, this study showed that identifying the delta-32 mutation of the CCR5 gene using HRM assay is not as straightforward as previously suggested in some literature, and it requires special setup conditions.
Authors
- Tahereh Donyavi (ORCID: https://orcid.org/0000-0002-8502-2780)
- Seyed Jalal Kiani (ORCID: https://orcid.org/0000-0002-5499-8924)
- Farah Bokharaei‐Salim (ORCID: https://orcid.org/0000-0002-5367-0847)
Institutions
- Iran University of Medical Sciences (IR)
Publication Details
- Journal
- Current HIV Research
- Published
- 2024-09-16
- DOI
- https://doi.org/10.2174/011570162x326491240906064322
- Citations
- 1
- Primary Topic
- HIV Research and Treatment
- Type
- article
- Field-Weighted Citation Impact
- 0.29