The impact of margins and re‐resection in pediatric synovial sarcoma
This study re-affirms that R0 resection is an independent prognostic predictor of better OS/EFS in pediatric synovial sarcoma. Second, our study extends this finding to report negative margins on initial resection or re-resection is associated with better OS/EFS than positive margins on initial resection or re-resection. Lastly, we found that there is no difference in outcomes associated with re-resection or <5 mm margins for R0 patients, indicating that re-resection and <5 mm margins are acceptable if microscopic disease is removed.
Authors
- Dai H. Chung (ORCID: https://orcid.org/0000-0001-7044-940X)
- M. Fatih Okcu (ORCID: https://orcid.org/0000-0001-9492-8675)
- Hannah Todd (ORCID: https://orcid.org/0000-0002-1568-8085)
- Nicole I. Montgomery
- Andres F. Espinoza (ORCID: https://orcid.org/0000-0001-8716-3125)
- Rajkumar Venkatramani (ORCID: https://orcid.org/0000-0002-4785-106X)
- Eumenia Castro (ORCID: https://orcid.org/0000-0002-8959-2414)
- Jillian C. Jacobson (ORCID: https://orcid.org/0000-0002-7234-9303)
- John J. Doski (ORCID: https://orcid.org/0000-0003-4417-0696)
- Sanjeev A. Vasudevan (ORCID: https://orcid.org/0000-0003-3578-4258)
- Priya B. Shetty (ORCID: https://orcid.org/0000-0002-2086-3319)
- Kelley Harrell
- Alfred F. Trappey
Institutions
- Baylor College of Medicine (US)
- Texas Children's Hospital (US)
- Children's Cancer Center (US)
- The University of Texas at San Antonio (US)
- The University of Texas Southwestern Medical Center (US)
Publication Details
- Journal
- Cancer Medicine
- Published
- 2024-09-01
- DOI
- https://doi.org/10.1002/cam4.70207
- Citations
- 6
- Primary Topic
- Sarcoma Diagnosis and Treatment
- Type
- article
- Field-Weighted Citation Impact
- 2.51
Funders
- Cancer Prevention and Research Institute of Texas
- University of Texas at San Antonio
- Macy Easom Cancer Research Foundation