[Conbercept reverses TGF-β<sub>2</sub>-induced epithelial-mesenchymal transition in human lens epithelial cells by regulating the TGF-β/Smad signaling pathway].
Conbercept inhibits TGF-β<sub>2</sub> induced EMT by downregulating the expression of pSmad2/3 in TGF-β/Smad signaling pathway, indicating a potential therapeutic strategy against visual loss induced by posterior capsule opacification.
Authors
- Mingjun Zhu (ORCID: https://orcid.org/0000-0001-7646-6577)
- J Wang
Institutions
- Bengbu Medical College (CN)
- Fuyang Maternity and Child Health Care Hospital (CN)
- First Affiliated Hospital of Bengbu Medical College (CN)
- Fuyang Second People's Hospital (CN)
Publication Details
- Journal
- PubMed
- Published
- 2024-08-20
- DOI
- https://doi.org/10.12122/j.issn.1673-4254.2024.08.04
- Primary Topic
- TGF-β signaling in diseases
- Type
- article