[Platelet-specific <i>Rictor</i> knockout inhibits platelet production and activation and reduces thrombosis in mice].
Platelet-specific <i>Rictor</i> knockout inhibits platelet generation and activation to result in decreased thrombus formation in mice, suggesting the potential of mTORC2 activity inhibition as an efficient antithrombotic strategy.
Authors
- Long Qian (ORCID: https://orcid.org/0000-0002-4892-6588)
- Jingjing Yang (ORCID: https://orcid.org/0000-0001-8521-7492)
- A Liu (ORCID: https://orcid.org/0009-0004-7493-4620)
Institutions
- Southern Medical University (CN)
Publication Details
- Journal
- PubMed
- Published
- 2024-08-20
- DOI
- https://doi.org/10.12122/j.issn.1673-4254.2024.08.20
- Primary Topic
- Antiplatelet Therapy and Cardiovascular Diseases
- Type
- article