[Swertiamarin ameliorates 2, 4, 6-trinitrobenzenesulfonic acid-induced colitis in mice by inhibiting intestinal epithelial cell apoptosis].
STM inhibits intestinal epithelial cell apoptosis at least in part by suppressing activation of the PI3K/AKT pathway to ameliorate intestinal barrier dysfunction and colitis in mice.
Authors
- Xiaoshan Wu (ORCID: https://orcid.org/0000-0002-7003-0884)
- J. Li (ORCID: https://orcid.org/0000-0001-5245-2074)
- Sheng Liu (ORCID: https://orcid.org/0000-0002-4483-4512)
Institutions
- Bengbu Medical College (CN)
- Anhui Medical University (CN)
- First Affiliated Hospital of Anhui Medical University (CN)
- First Affiliated Hospital of Bengbu Medical College (CN)
Publication Details
- Journal
- PubMed
- Published
- 2024-08-20
- DOI
- https://doi.org/10.12122/j.issn.1673-4254.2024.08.13
- Primary Topic
- Inflammatory mediators and NSAID effects
- Type
- article