[Tujia medicine <i>Toddalia asiatica</i> improves synovial pannus in rats with collagen-induced arthritis through the PI3K/Akt signaling pathway].
TAAE can improve joint symptoms and inhibit synovial pannus formation in CIA rats by regulating the expressions of HIF-1α, VEGF, endostatin, MMP1, MMP3, and MMP9 via the PI3K/Akt signalling pathway.
Authors
- Ren‐Rong Tian
- De‐Pei Liu (ORCID: https://orcid.org/0000-0002-2636-4297)
- Dongmei Cheng (ORCID: https://orcid.org/0000-0002-4638-0884)
- Bao Zhang (ORCID: https://orcid.org/0000-0003-0320-2305)
- Zhihui Zhang (ORCID: https://orcid.org/0000-0003-3111-2665)
- Wenli Li (ORCID: https://orcid.org/0000-0003-1598-3217)
- Jiang Lin (ORCID: https://orcid.org/0000-0002-4704-9157)
- Yuan Liang (ORCID: https://orcid.org/0000-0002-3098-9337)
- Shiyin Xiang
Institutions
- Minzu University of China (CN)
Publication Details
- Journal
- PubMed
- Published
- 2024-08-20
- DOI
- https://doi.org/10.12122/j.issn.1673-4254.2024.08.17
- Primary Topic
- Ethics in medical practice
- Type
- article