[ORY-1001 inhibits glioblastoma cell growth by downregulating the Notch/HES1 pathway <i>via</i> suppressing lysine-specific demethylase 1 expression].
ORY-1001 down-regulates the Notch/HES1 pathway by inhibiting LSD1 expression to suppress the growth of GBM in mice.
Authors
- Yi Xiang (ORCID: https://orcid.org/0000-0002-1154-5802)
- Yunlong Lei (ORCID: https://orcid.org/0000-0002-7918-0221)
- Tingting Tan
- Huan Yang (ORCID: https://orcid.org/0000-0003-1863-1524)
Institutions
- Fuyang City People's Hospital (CN)
- The Affiliated Yongchuan Hospital of Chongqing Medical University (CN)
- Chongqing Medical University (CN)
Publication Details
- Journal
- PubMed
- Published
- 2024-08-20
- DOI
- https://doi.org/10.12122/j.issn.1673-4254.2024.08.22
- Citations
- 1
- Primary Topic
- MicroRNA in disease regulation
- Type
- article