[Analysis of core functional components in <i>Yinchenhao</i> Decoction and their pathways for treating liver fibrosis].
The therapeutic effect of YCHD on hepatic fibrosis is probably mediated by its core functional components including benzyl acetate, vanillic acid, clorius, polydatin, lauric acid and ferulic acid, which inhibit the PI3K-AKT and MAPK pathways in hepatic stellate cells.
Authors
- Daogang Guan (ORCID: https://orcid.org/0000-0003-1414-0189)
- Qifa Liu (ORCID: https://orcid.org/0000-0003-4015-3952)
- Ke Ma (ORCID: https://orcid.org/0000-0003-4942-9281)
- Yuan Li (ORCID: https://orcid.org/0000-0001-9004-5146)
- Xiaojun Chen (ORCID: https://orcid.org/0000-0002-5493-1500)
- Qin Fan (ORCID: https://orcid.org/0000-0002-7196-8145)
- Zhibo Zhu (ORCID: https://orcid.org/0000-0002-6332-9407)
- Xiaomei Zhong (ORCID: https://orcid.org/0000-0001-9846-1400)
- Limei Luo (ORCID: https://orcid.org/0000-0001-7299-3628)
Institutions
- TCM-Intigrated Cancer Center of Southern Medical University (CN)
- Southern Medical University (CN)
Publication Details
- Journal
- PubMed
- Published
- 2024-08-20
- DOI
- https://doi.org/10.12122/j.issn.1673-4254.2024.08.09
- Primary Topic
- Liver physiology and pathology
- Type
- article