A comprehensive analysis of Cestrum nocturnum: Its phytochemical composition, pharmacological applications, and toxicity profile in the context of traditional medicinal practices

According to traditional medicine, the study gives a full look at the phytochemical makeup, pharmacological uses, and toxic profile of Cestrum nocturnum (night-blooming jasmine). The review sought to connect traditional knowledge with scientific evidence, assessing the therapeutic potential and safety concerns linked to this plant. The methods involved conducting a comprehensive search of peer-reviewed literature and ethnobotanical databases. The focus was on studies that examined the chemical composition, pharmacological effects, and toxicological properties of Cestrum nocturnum. The data pertaining to traditional uses, active compounds, therapeutic effects, dosage, and adverse reactions were thoroughly extracted and carefully analyzed. The results indicate that Cestrum nocturnum contains a range of phytochemicals, such as alkaloids, glycosides, flavonoids, and essential oils. Pharmacological studies have extensively documented its various effects, including anti-inflammatory, analgesic, antimicrobial, anticonvulsant, and sedative properties. Common applications involve the treatment of ailments like epilepsy, anxiety, and skin disorders. Nevertheless, there have been some concerns raised about the plant's toxicity, specifically related to the presence of solanine alkaloids. In conclusion, Cestrum nocturnum shows great potential as a source of bioactive compounds that could have valuable therapeutic applications. However, more research is needed, including thorough clinical trials and toxicity assessments, to determine the safety and effectiveness of this treatment for specific conditions. This review highlights the significance of combining traditional knowledge with scientific validation to fully harness the potential of Cestrum nocturnum in modern medicine, while also prioritizing its safe and responsible utilization. Keywords: Cestrum nocturnum, phytochemistry, pharmacology, toxicology, traditional medicine