Evaluation of the effect of taurine on the matrix metalloproteinase-9 and the expression changes of miRNA-21 and miRNA-146a in SH-SY5Y cell line
Our study revealed that taurine can alter the expression of miRNA-146a and miRNA-21. In conclusion, taurine therapy presents promising therapeutic avenues for treating AD or mitigating severe symptoms. Nonetheless, further research is necessary to comprehensively grasp the precise mechanisms at play.
Authors
- Mohanad Ali Abdulhadi (ORCID: https://orcid.org/0000-0001-9846-9760)
- Muna S. Merza (ORCID: https://orcid.org/0000-0003-3642-2718)
- Bilal Abdulmajeed mukhlif
- Sami Awad Alkubaisy
- Karrar R. Al-Shami
- Abduladheem AL-Attabi (ORCID: https://orcid.org/0000-0001-8403-7465)
Institutions
- University of Babylon (IQ)
- Thi Qar University (IQ)
- University of Anbar (IQ)
- University of Al Maarif (IQ)
- National University of Science and Technology (ZW)
- Al-Mustaqbal University
Publication Details
- Journal
- Hormone Molecular Biology and Clinical Investigation
- Published
- 2024-09-15
- DOI
- https://doi.org/10.1515/hmbci-2024-0005
- Primary Topic
- Aldose Reductase and Taurine
- Type
- article
- Field-Weighted Citation Impact
- 0.00