Serum and urinary levels of MIF, CD74, DDT and CXCR4 among patients with type 1 diabetes mellitus, type 2 diabetes and healthy individuals: Implications for further research
The increased serum MIF levels and urinary CD74 levels among patients with T1DM may be attributed to the autoimmune milieu, which characterises patients with T1DM, when compared to patients with T2DM. These two findings merit further attention as they could pave the way for further research regarding the potential beneficial effects of inhibitors of MIF among patients with T1DM, especially in the early stages of T1DM. Finally, the role of inhibitors of MIF could be further explored in the context of obesity among patients with T2DM.
Authors
- Fotis Panagopoulos (ORCID: https://orcid.org/0009-0002-6864-9570)
- Μaria Dalamaga (ORCID: https://orcid.org/0000-0002-7008-388X)
- Paolo Fagone (ORCID: https://orcid.org/0000-0002-6694-1992)
- Dimitris Kounatidis (ORCID: https://orcid.org/0000-0003-4338-4879)
- Katia Mangano (ORCID: https://orcid.org/0000-0001-5920-4620)
- Natalia G. Vallianou (ORCID: https://orcid.org/0000-0003-3874-5393)
- Aristidis Diamantopoulos
- Theodora Stratigou (ORCID: https://orcid.org/0000-0003-3186-7099)
- Ferdinando Nicoletti (ORCID: https://orcid.org/0000-0002-4570-8462)
Institutions
- National and Kapodistrian University of Athens (GR)
- University of Catania (IT)
- Evangelismos Hospital (GR)
Publication Details
- Journal
- Metabolism Open
- Published
- 2024-09-15
- DOI
- https://doi.org/10.1016/j.metop.2024.100320
- Citations
- 10
- Primary Topic
- Macrophage Migration Inhibitory Factor
- Type
- article
- Field-Weighted Citation Impact
- 2.40