Two New Compounds from Arctium lappa Roots
A new caffeoylquinic acid, 1, 5-di-O-caffeoyl-3-O-(1-O-methoxy-2-O-caffeoyl-4-maloyl)-quinic acid (1), and a new 5-hydroxymethylfurfural dimer, 5-(((2-methoxymethyl) furan-5-methanol) methyl) furan-2carbaldehyde (2), were discovered from Arctium lappa roots.A comprehensive HRMS, UV, IR, 1D and 2D NMR techniques were used for structural identification.These two compounds had Nitric Oxide (NO) inhibitory activity in lipopolysaccharide (LPS)-stimulated RAW 264.7 inflammatory cell in a dose-dependent manner.
Authors
- Lingxia Zhang (ORCID: https://orcid.org/0000-0002-5012-7283)
- Liping Dai (ORCID: https://orcid.org/0000-0002-1910-7591)
- Jun Chi (ORCID: https://orcid.org/0000-0002-9325-1196)
- Zhimin Wang (ORCID: https://orcid.org/0000-0001-9039-715X)
- Weijin Zhang (ORCID: https://orcid.org/0000-0002-1477-7465)
- Qingyu Yang
Publication Details
- Journal
- Records of Natural Products
- Published
- 2024-09-15
- DOI
- https://doi.org/10.25135/rnp.474.2404.3187
- Citations
- 1
- Primary Topic
- Plant-derived Lignans Synthesis and Bioactivity
- Type
- article
- Field-Weighted Citation Impact
- 0.23
Funders
- National Natural Science Foundation of China