Causal associations between circulating immune cells and osteoarthritis: A bidirectional mendelian randomization study
Our study has demonstrated the causal associations between multiple immune cells and diverse joint OA. These results highlight the intricate interplay between immune cells and OA, suggesting potential targets for therapeutic interventions to manage disease progression and alleviate symptoms.
Authors
- Zhengyi Ni
- Chenyue Xu (ORCID: https://orcid.org/0000-0002-8484-3181)
- Gang Ji (ORCID: https://orcid.org/0000-0001-8535-2635)
- Xiaobo Chen (ORCID: https://orcid.org/0000-0001-9180-0190)
- Shengjie Wang (ORCID: https://orcid.org/0000-0001-8467-3031)
- Tianhang Zhang
- Fei Wang (ORCID: https://orcid.org/0000-0001-6344-1872)
Institutions
- Hebei Medical University (CN)
- Third Hospital of Hebei Medical University (CN)
- Harrison International Peace Hospital (CN)
Publication Details
- Journal
- International Immunopharmacology
- Published
- 2024-09-15
- DOI
- https://doi.org/10.1016/j.intimp.2024.113156
- Citations
- 12
- Primary Topic
- Osteoarthritis Treatment and Mechanisms
- Type
- article
- Field-Weighted Citation Impact
- 5.64
Funders
- National Natural Science Foundation of China
- Natural Science Foundation of Hebei Province
- Hebei Province Graduate Innovation Funding Project