Development of Influenza-Specific CD4 T Cell-Mediated Immunity in Children Following Inactivated Influenza Vaccination
Inactivated influenza vaccine elicits a CD4 T cell response to H3 and HAB, with increases in the magnitude of the CD4 T cell response and changes in cellular functionality throughout childhood. This suggests that repeated influenza vaccination contributes to the development of anti-influenza CD4 T cell memory in children.
Authors
- Jennifer L. Nayak (ORCID: https://orcid.org/0000-0002-5042-3031)
- Nelson Huertas
- Ian Shannon
- Hongmei Yang (ORCID: https://orcid.org/0000-0002-6535-2862)
- Chantelle L. White
Institutions
- University of Rochester Medical Center (US)
Publication Details
- Journal
- Journal of the Pediatric Infectious Diseases Society
- Published
- 2024-09-12
- DOI
- https://doi.org/10.1093/jpids/piae095
- Citations
- 1
- Primary Topic
- Influenza Virus Research Studies
- Type
- article
- Field-Weighted Citation Impact
- 0.39
Funders
- University of Rochester