Impact of Baseline SARS-CoV-2 Load in Plasma and Upper Airways on the Incidence of Acute Extrapulmonary Complications of COVID-19: A Multicentric, Prospective, Cohort Study
Systemic viral dissemination as evidenced by high plasma N-Ag level and high respiratory viral burden are associated with development of EPCs in COVID-19, which in turn are associated with higher 90-day mortality rates.
Authors
- Shaili Gupta (ORCID: https://orcid.org/0000-0001-9508-0995)
- Kathryn Shaw‐Saliba (ORCID: https://orcid.org/0000-0002-4396-2432)
- Robin Dewar (ORCID: https://orcid.org/0000-0002-7840-3155)
- Aliasgar Esmail (ORCID: https://orcid.org/0000-0002-1835-9252)
- Sarah Pett (ORCID: https://orcid.org/0000-0002-4851-4727)
- Nila J. Dharan (ORCID: https://orcid.org/0000-0003-1175-5962)
- Jason V. Baker (ORCID: https://orcid.org/0000-0002-5542-1545)
- Tomas Ø. Jensen (ORCID: https://orcid.org/0000-0003-0398-4431)
- David M. Vock (ORCID: https://orcid.org/0000-0002-5459-9579)
- Minh Q Ho (ORCID: https://orcid.org/0000-0001-7509-6156)
- Katrina Harper
- Sean Liu (ORCID: https://orcid.org/0000-0002-3842-6838)
- Jens Dilling Lundgren (ORCID: https://orcid.org/0000-0001-8901-7850)
- Eyad Almasri
Institutions
- University of Copenhagen (DK)
- University of Minnesota (US)
- University of Cape Town (ZA)
- University of California, San Francisco (US)
- Rigshospitalet (DK)
- UNSW Sydney (AU)
- Yale University (US)
- VA Connecticut Healthcare System (US)
- MRC Clinical Trials Unit at UCL (GB)
- Lung Institute (US)
- South African Tuberculosis Vaccine Initiative (ZA)
- New South Wales Institute of Psychiatry (AU)
- Frederick National Laboratory for Cancer Research (US)
- Orlando VA Medical Center (US)
- National Institute of Allergy and Infectious Diseases (US)
- Hennepin Healthcare Research Institute (US)
- Centre of Excellence for Health, Immunity and Infections (DK)
- University College London (GB)
- California State University, Fresno (US)
- Medical Research Council (GB)
- Icahn School of Medicine at Mount Sinai (US)
Publication Details
- Journal
- Clinical Infectious Diseases
- Published
- 2024-09-12
- DOI
- https://doi.org/10.1093/cid/ciae469
- Citations
- 4
- Primary Topic
- COVID-19 Clinical Research Studies
- Type
- article
- Field-Weighted Citation Impact
- 1.56
Funders
- Medical Research Council