Computer Vision Meets Large Language Models: Performance of ChatGPT 4.0 on Dermatology Boards-Style Practice Questions

Background: ChatGPT is a generative artificial intelligence that has numerous professional applications. Applications in medical education are currently being explored. ChatGPT 4.0 performance on image-based dermatology boards-style practice questions has not been assessed. Objective: The objective of this study was to determine the accuracy with which ChatGPT can answer dermatology boards examination practice questions. Methods: 150 multiple-choice questions from the popular question bank DermQbank were inputted into ChatGPT. Of these, 83 were text-only questions and 67 had associated images. These same questions were inputted into ChatGPT again in July 2024. An additional 150 questions were inputted for a total of 300 different questions where 169 were text-only and 133 had associated images. Results: Of the aggregate 300 question data, ChatGPT answered 232 questions correctly (77.3%). ChatGPT performed significantly better with text-only questions than with questions that included images (85.2% (144/169) vs 67.7% (90/133), P<.001). Of image-based questions, ChatGPT performed better with clinical image questions than with dermatopathology questions (69.0% (78/133) vs. 58.8% (10/17), P=.40), but this difference was not statistically significant partially due to the sample size of the dermatopathology questions. Compared to post-graduate year 4 (PGY-4) residents, ChatGPT performed above the 46th percentile. ChatGPT agreed with the answer choice picked by the majority of question bank users 75.3% of the time. Multivariable regression demonstrated that significant predictive variables for ChatGPT answering a question correctly included the percent of dermatology trainees who answered a question correctly and whether the question was text-based (P<.001and P=.004, respectively). Conclusions: ChatGPT answered 77.3% of dermatology board examination practice questions correctly, performing above the 46th percentile of PGY-4 question bank users. If using ChatGPT as a study resource for dermatology board examination preparation, residents should be judicious with exactly how they employ ChatGPT to avoid learning incorrect information.