Research biopsies in kidney transplantation: an evaluation of surgical techniques and optimal tissue mass allowing molecular and histological analyses
The 2 mm punch biopsy has been shown to be challenging to use and frequently provides inadequate tissue for histology and proteomics while 3 mm research biopsies were the smallest size that were technically obtainable with adequate tissue for molecular studies.
Authors
- James Hunter (ORCID: https://orcid.org/0000-0001-9524-0629)
- Hannah McGivern (ORCID: https://orcid.org/0000-0003-3436-1536)
- Jesper Kers (ORCID: https://orcid.org/0000-0002-2418-5279)
- Rutger J. Ploeg (ORCID: https://orcid.org/0000-0001-7801-665X)
- Sadr ul Shaheed
- Syed Hussain Abbas (ORCID: https://orcid.org/0000-0002-9434-2970)
- Ka Ho Tam (ORCID: https://orcid.org/0000-0003-4973-098X)
- Corinna Snashall (ORCID: https://orcid.org/0000-0002-8418-9722)
- S. E. Cross (ORCID: https://orcid.org/0000-0003-3674-3503)
- Chris W. Sutton (ORCID: https://orcid.org/0000-0002-1548-5093)
- Simon Knight (ORCID: https://orcid.org/0000-0003-4837-9446)
- Marta Oliveira (ORCID: https://orcid.org/0000-0002-8123-5471)
Institutions
- NHS Blood and Transplant (GB)
- University of Bradford (GB)
- Leiden University Medical Center (NL)
- Oxford Health NHS Foundation Trust (GB)
- John Radcliffe Hospital (GB)
- University of Oxford (GB)
- Oxford BioMedica (United Kingdom) (GB)
- Amsterdam University Medical Centers (NL)
- University of Amsterdam (NL)
Publication Details
- Journal
- Clinical Proteomics
- Published
- 2024-09-14
- DOI
- https://doi.org/10.1186/s12014-024-09508-2
- Primary Topic
- Molecular Biology Techniques and Applications
- Type
- article
- Field-Weighted Citation Impact
- 0.00
Funders
- NHS Blood and Transplant