Liver Characterization of a Cohort of Alpha-1 Antitrypsin Deficiency Patients with and without Lung Disease
Our data supports a relationship between the development of COPD and liver disease in AATD and introduces genes and pathways that may play a role in AATD liver disease when COPD is present. We believe addressing lung impairment and airway inflammation may be an approach to managing AATD-related liver disease.
Authors
- Virginia Clark (ORCID: https://orcid.org/0000-0001-6719-3634)
- Jorge Lascano (ORCID: https://orcid.org/0000-0002-9546-1867)
- Regina Oshins
- Mark Brantly (ORCID: https://orcid.org/0000-0003-0189-1565)
- George Marek (ORCID: https://orcid.org/0000-0002-2995-3660)
- Nazli Khodayari (ORCID: https://orcid.org/0000-0002-4659-1622)
- Tongjun Gu (ORCID: https://orcid.org/0000-0002-8379-0962)
- Naziheh Assarzadegan (ORCID: https://orcid.org/0000-0002-3368-3202)
- N. Mohammad
Institutions
- University of Florida (US)
- Mayo Clinic in Arizona (US)
- Florida College (US)
Publication Details
- Journal
- Journal of Clinical and Translational Hepatology
- Published
- 2024-09-14
- DOI
- https://doi.org/10.14218/jcth.2024.00201
- Citations
- 2
- Primary Topic
- Protease and Inhibitor Mechanisms
- Type
- article
- Field-Weighted Citation Impact
- 0.57