Quantitative SPECT imaging of 155Tb and 161Tb for preclinical theranostic radiopharmaceutical development
Both <sup>155</sup>Tb and <sup>161</sup>Tb demonstrated potential for applications in preclinical quantitative SPECT imaging. The high-resolution collimator achieves < 0.85 mm resolution and maintains quantitative accuracy in small volumes which is advantageous for assessing sub organ activity distributions in small animals. This imaging method can provide critical quantitative information for assessing and optimizing preclinical Tb-radiopharmaceuticals.
Authors
- Aidan Ingham (ORCID: https://orcid.org/0000-0001-6917-0161)
- Valery Radchenko (ORCID: https://orcid.org/0000-0002-4742-6565)
- Arman Rahmim (ORCID: https://orcid.org/0000-0002-9980-2403)
- Cristina Rodríguez‐Rodríguez (ORCID: https://orcid.org/0000-0002-3313-4422)
- Paul Schaffer
- Maarten Ooms (ORCID: https://orcid.org/0000-0002-7489-1630)
- Peter Kunz (ORCID: https://orcid.org/0000-0001-5842-4648)
- Michiel Van de Voorde (ORCID: https://orcid.org/0000-0002-1176-9056)
- Carlos Uribe (ORCID: https://orcid.org/0000-0003-3127-7478)
- Helena Koniar (ORCID: https://orcid.org/0000-0003-0794-9115)
- Scott McNeil (ORCID: https://orcid.org/0000-0001-8121-8471)
- Luke Wharton (ORCID: https://orcid.org/0000-0002-0636-8741)
- Hua Yang (ORCID: https://orcid.org/0000-0001-7706-9020)
- Sathiya Sekar
Institutions
- BC Cancer Agency (CA)
- TRIUMF (CA)
- University of British Columbia (CA)
- Simon Fraser University (CA)
- Belgian Nuclear Research Centre (BE)
Publication Details
- Journal
- EJNMMI Physics
- Published
- 2024-09-14
- DOI
- https://doi.org/10.1186/s40658-024-00682-8
- Citations
- 13
- Primary Topic
- Radiopharmaceutical Chemistry and Applications
- Type
- article
- Field-Weighted Citation Impact
- 5.26
Funders
- Canada Foundation for Innovation
- National Research Council Canada