B - 122 A Preliminary Analysis of the Neuropsychological Evaluation of the UPSA (NEUPSA)

Abstract Objective The UCSD Performance Skills Assessment (UPSA) is a well-established performance instrument created to evaluate functional outcomes. We applied a neuropsychological framework to the UPSA and created the Neuropsychological Evaluation of the UPSA (NEUPSA), assessing the cognitive processes that underlie the functional tasks in the UPSA. The study aimed to compare the executive function and attention components of the NEUPSA with a validated computerized cognitive assessment. Methods Participants were 86 adults drawn from the San Diego community. Participants completed the UPSA, 5 Choice CPT (5CCPT) which evaluates attention by calculating a d-prime score that assesses sustained attention, and the Iowa Gambling Task (IGT) which assesses risky decision making. We employed a Spearman’s correlation analysis with a 95% confidence interval to assess the strength of the relationship between NEUPSA attention scores and 5CCPT and IGT performance. Results NEUPSA subscores were significantly correlated with performance on computerized cognitive assessments. 5CCPT scores were positively correlated with NEUPSA attention scores (r = 0.24, p = 0.03). IGT scores were positively correlated with NEUPSA executive functioning scores (r = 0.23, p = 0.04). Conclusion These findings provide preliminary evidence that the NEUPSA assesses aspects of attention (i.e., sustained attention) and executive function (i.e., risky decision making). Further research, however, needs to be conducted on the validity of this measure and the utility in assessing neuropsychological function in clinical populations. Next steps include assessing NEUPSA performance in various non-healthy comparison populations. In this study, we emphasize the fundamental cognitive principles necessary for performance, offering a promising avenue for comprehending impaired functioning.