Abnormal circadian rhythms exacerbate dilated cardiomyopathy by reducing the ventricular mechanical strength
Compared with the non-SA group, left ventricular (LV) wall dilation was more severe and the structural strength was lower in DCM patients with SA, and phenotypic changes in CM and Fib were involved in this process. ACR-DCM was histopathologically characterized by a structurally weak ventricular wall.
Authors
- Xiumeng Hua (ORCID: https://orcid.org/0009-0006-5424-8812)
- Lei Han (ORCID: https://orcid.org/0000-0002-7535-7915)
- Hao Cui (ORCID: https://orcid.org/0000-0001-7634-748X)
- Jiangping Song (ORCID: https://orcid.org/0000-0002-9488-7823)
- Hao Jia (ORCID: https://orcid.org/0000-0002-4736-0957)
- Zhibo Shentu (ORCID: https://orcid.org/0009-0007-1728-7713)
- Ningning Zhang (ORCID: https://orcid.org/0000-0001-6744-3867)
- Yulin Chen (ORCID: https://orcid.org/0000-0001-5679-4055)
- Zijie Zhao (ORCID: https://orcid.org/0009-0004-9482-8315)
- Chen Xiao (ORCID: https://orcid.org/0000-0002-0287-8330)
- Han Mo (ORCID: https://orcid.org/0000-0003-1834-1746)
- Mengda Xu
- Yu Zhang (ORCID: https://orcid.org/0009-0009-4844-3867)
- Tie Xia
- Yue Zhang (ORCID: https://orcid.org/0000-0002-8439-1488)
- Siyuan Huang
- Yuan Chang (ORCID: https://orcid.org/0009-0008-2239-7383)
Institutions
- Chinese Academy of Medical Sciences & Peking Union Medical College (CN)
- Kunming Medical University (CN)
- Gansu University of Traditional Chinese Medicine (CN)
- Center for Life Sciences (CN)
- Fu Wai Hospital (CN)
- Tsinghua University (CN)
Publication Details
- Journal
- Cardiovascular Research
- Published
- 2024-09-13
- DOI
- https://doi.org/10.1093/cvr/cvae212
- Citations
- 5
- Primary Topic
- Cardiovascular Disease and Adiposity
- Type
- article
- Field-Weighted Citation Impact
- 2.01
Funders
- National Natural Science Foundation of China
- Tsinghua University