Exploring resveratrol against Alzheimer's disease and Parkinson's disease through integrating network pharmacology, bioinformatics, and experimental validation strategy in vitro
Resveratrol may play a potential mechanism of "treating the same disease with different diseases" and target three core targets (PLK4, FCGRT and PRKAR2A) to improve the disease process of AD and PD by participating in the regulation of immune and inflammatory pathways. These findings have potential implications for clinical practice and future research.
Authors
- Chengcheng He (ORCID: https://orcid.org/0000-0002-5855-9611)
- Boxue Wang
- Jian Liu (ORCID: https://orcid.org/0000-0001-8552-1400)
- Weimin Zhao
- R. Bi (ORCID: https://orcid.org/0000-0001-7977-7776)
- Naixin Zhan
- Jinpu Wu
- Ziyue Tian
- Daixuan Song
Institutions
- Jilin University (CN)
- First Hospital of Jilin University (CN)
- Changchun University of Chinese Medicine (CN)
- Hainan General Hospital (CN)
- The Affiliated Hospital to Changchun University of Chinese Medicine (CN)
Publication Details
- Journal
- Heliyon
- Published
- 2024-09-01
- DOI
- https://doi.org/10.1016/j.heliyon.2024.e37908
- Citations
- 7
- Primary Topic
- Sirtuins and Resveratrol in Medicine
- Type
- article
- Field-Weighted Citation Impact
- 2.41
Funders
- Jilin Scientific and Technological Development Program